Ontology highlight
ABSTRACT:
SUBMITTER: Wiederin JL
PROVIDER: S-EPMC3285256 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Wiederin Jayme L JL Donahoe Robert M RM Anderson James R JR Yu Fang F Fox Howard S HS Gendelman Howard E HE Ciborowski Pawel S PS
Journal of proteome research 20100901 9
Lentiviral replication in its target cells affects a delicate balance between cellular cofactors required for virus propagation and immunoregulation for host defense. To better elucidate cellular proteins linked to viral infection, we tested plasma from rhesus macaques infected with the simian immunodeficiency viral strain SIVsmm9, prior to, 10 days (acute), and 49 weeks (chronic) after viral infection. Changes in plasma protein content were measured by quantitative mass spectrometry by isobaric ...[more]