Ontology highlight
ABSTRACT:
SUBMITTER: Reid DW
PROVIDER: S-EPMC3285328 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Reid David W DW Nicchitta Christopher V CV
The Journal of biological chemistry 20111223 8
In eukaryotic cells, the spatial regulation of protein expression is frequently conferred through the coupling of mRNA localization and the local control of translation. mRNA localization to the endoplasmic reticulum (ER) is a prominent example of such regulation and serves a ubiquitous role in segregating the synthesis of secretory and integral membrane proteins to the ER. Recent genomic and biochemical studies have now expanded this view to suggest a more substantial role for the ER cellular p ...[more]