Ontology highlight
ABSTRACT:
SUBMITTER: Villar-Garea A
PROVIDER: S-EPMC3287205 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Villar-Garea Ana A Forne Ignasi I Vetter Irene I Kremmer Elisabeth E Thomae Andreas A Imhof Axel A
Nucleic acids research 20111103 4
Histone post-translational modifications play an important role in regulating chromatin structure and gene expression in vivo. Extensive studies investigated the post-translational modifications of the core histones H3 and H4 or the linker histone H1. Much less is known on the regulation of H2A and H2B modifications. Here, we show that a major modification of H2B in Drosophila melanogaster is the methylation of the N-terminal proline, which increases during fly development. Experiments performed ...[more]