Ontology highlight
ABSTRACT:
SUBMITTER: Shestopalov IA
PROVIDER: S-EPMC3288381 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Nature chemical biology 20120129 3
Transcription factors have diverse roles during embryonic development, combinatorially controlling cellular states in a spatially and temporally defined manner. Resolving the dynamic transcriptional profiles that underlie these patterning processes is essential for understanding embryogenesis at the molecular level. Here we show how temporal, tissue-specific changes in embryonic transcription factor function can be discerned by integrating caged morpholino oligonucleotides with photoactivatable ...[more]