Ontology highlight
ABSTRACT:
SUBMITTER: Yin WB
PROVIDER: S-EPMC3288630 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Yin Wen-Bing WB Amaike Saori S Wohlbach Dana J DJ Gasch Audrey P AP Chiang Yi-Ming YM Wang Clay C C CC Bok Jin Woo JW Rohlfs Marko M Keller Nancy P NP
Molecular microbiology 20120210 5
The eukaryotic bZIP transcription factors are critical players in organismal response to environmental challenges. In fungi, the production of secondary metabolites (SMs) is hypothesized as one of the responses to environmental insults, e.g. attack by fungivorous insects, yet little data to support this hypothesis exists. Here we establish a mechanism of bZIP regulation of SMs through RsmA, a recently discovered YAP-like bZIP protein. RsmA greatly increases SM production by binding to two sites ...[more]