Ontology highlight
ABSTRACT:
SUBMITTER: Maredia R
PROVIDER: S-EPMC3289957 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
TheScientificWorldJournal 20120214
Bacterial infections can be aggravated by antibiotic treatment that induces SOS response and vesiculation. This leads to a hypothesis concerning association of SOS with vesiculation. To test it, we conducted multiple analyses of outer membrane vesicles (OMVs) produced from the Pseudomonas aeruginosa wild type in which SOS is induced by ciprofloxacin and from the LexA noncleavable (lexAN) strain in which SOS is repressed. The levels of OMV proteins, lipids, and cytotoxicity increased for both the ...[more]