Ontology highlight
ABSTRACT:
SUBMITTER: Day-Williams AG
PROVIDER: S-EPMC3290352 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Genetic epidemiology 20110404 5
The need to collect accurate and complete pedigree information has been a drawback of family-based linkage and association studies. Even in case-control studies, investigators should be aware of, and condition on, familial relationships. In single nucleotide polymorphism (SNP) genome scans, relatedness can be directly inferred from the genetic data rather than determined through interviews. Various methods of estimating relatedness have previously been implemented, most notably in PLINK. We pres ...[more]