Ontology highlight
ABSTRACT:
SUBMITTER: Yang J
PROVIDER: S-EPMC3290520 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Yang Jun J Schmelzer Kara K Georgi Katrin K Hammock Bruce D BD
Analytical chemistry 20091001 19
Cyclooxygenase, lipoxygenase, and epoxygenase derived oxylipins, especially eicosanoids, play important roles in many physiological processes. Assessment of oxidized fatty acid levels is important for understanding their homeostatic and pathophysiological roles. Most reported methods examine these pathways in isolation. The work described here employed a solid phase extraction-liquid chromatography-electrospray ionization MS/MS (SPE-LC-ESI MS/MS) method to monitor these metabolites. In 21 min, 3 ...[more]