Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC3292301 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Li Chenggang C Yang Penghui P Sun Yang Y Li Taisheng T Wang Chen C Wang Zhong Z Zou Zhen Z Yan Yiwu Y Wang Wei W Wang Chen C Chen Zhongwei Z Xing Li L Tang Chong C Ju Xiangwu X Guo Feng F Deng Jiejie J Zhao Yan Y Yang Peng P Tang Jun J Wang Huanling H Zhao Zhongpeng Z Yin Zhinan Z Cao Bin B Wang Xiliang X Jiang Chengyu C
Cell research 20111025 3
The 2009 flu pandemic involved the emergence of a new strain of a swine-origin H1N1 influenza virus (S-OIV H1N1) that infected almost every country in the world. Most infections resulted in respiratory illness and some severe cases resulted in acute lung injury. In this report, we are the first to describe a mouse model of S-OIV virus infection with acute lung injury and immune responses that reflect human clinical disease. The clinical efficacy of the antiviral oseltamivir (Tamiflu) administere ...[more]