Ontology highlight
ABSTRACT:
SUBMITTER: Piehler AP
PROVIDER: S-EPMC3293240 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Piehler Armin P AP Ozcürümez Mustafa M Kaminski Wolfgang E WE
Frontiers in psychiatry 20120305
The A-subclass of ATP-binding cassette (ABC) transporters comprises 12 structurally related members of the evolutionarily highly conserved superfamily of ABC transporters. ABCA transporters represent a subgroup of "full-size" multispan transporters of which several members have been shown to mediate the transport of a variety of physiologic lipid compounds across membrane barriers. The importance of ABCA transporters in human disease is documented by the observations that so far four members of ...[more]