Unknown

Dataset Information

0

Evolution of diverse cell division and vesicle formation systems in Archaea.


ABSTRACT: Recently a novel cell division system comprised of homologues of eukaryotic ESCRT-III (endosomal sorting complex required for transport III) proteins was discovered in the hyperthermophilic crenarchaeote Sulfolobus acidocaldarius. On the basis of this discovery, we undertook a comparative genomic analysis of the machineries for cell division and vesicle formation in Archaea. Archaea possess at least three distinct membrane remodelling systems: the FtsZ-based bacterial-type system, the ESCRT-III-based eukaryote-like system and a putative novel system that uses an archaeal actin-related protein. Many archaeal genomes encode assortments of components from different systems. Evolutionary reconstruction from these findings suggests that the last common ancestor of the extant Archaea possessed a complex membrane remodelling apparatus, different components of which were lost during subsequent evolution of archaeal lineages. By contrast, eukaryotes seem to have inherited all three ancestral systems.

SUBMITTER: Makarova KS 

PROVIDER: S-EPMC3293450 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Evolution of diverse cell division and vesicle formation systems in Archaea.

Makarova Kira S KS   Yutin Natalya N   Bell Stephen D SD   Koonin Eugene V EV  

Nature reviews. Microbiology 20100906 10


Recently a novel cell division system comprised of homologues of eukaryotic ESCRT-III (endosomal sorting complex required for transport III) proteins was discovered in the hyperthermophilic crenarchaeote Sulfolobus acidocaldarius. On the basis of this discovery, we undertook a comparative genomic analysis of the machineries for cell division and vesicle formation in Archaea. Archaea possess at least three distinct membrane remodelling systems: the FtsZ-based bacterial-type system, the ESCRT-III-  ...[more]

Similar Datasets

| S-EPMC2596248 | biostudies-literature
| S-EPMC8054024 | biostudies-literature
| S-EPMC4858521 | biostudies-literature
| S-EPMC8131849 | biostudies-literature
| S-EPMC4121953 | biostudies-literature
| S-EPMC6736733 | biostudies-literature
| S-EPMC4453527 | biostudies-literature
| S-EPMC8131914 | biostudies-literature
| S-EPMC6364591 | biostudies-literature
| S-EPMC4823757 | biostudies-literature