Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe HC
PROVIDER: S-EPMC3293557 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Watanabe Hiroshi C HC Welke Kai K Schneider Franziska F Tsunoda Satoshi S Zhang Feng F Deisseroth Karl K Hegemann Peter P Elstner Marcus M
The Journal of biological chemistry 20120111 10
Channelrhodopsins (ChRs) are light-gated cation channels that mediate ion transport across membranes in microalgae (vectorial catalysis). ChRs are now widely used for the analysis of neural networks in tissues and living animals with light (optogenetics). For elucidation of functional mechanisms at the atomic level, as well as for further engineering and application, a detailed structure is urgently needed. In the absence of an experimental structure, here we develop a structural ChR model based ...[more]