Emergence of oseltamivir-resistant pandemic (H1N1) 2009 virus within 48 hours.
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ABSTRACT: An oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus evolved and emerged from zero to 52% of detectable virus within 48 hours of a patient's exposure to oseltamivir. Phylogenetic analysis and data gathered by pyrosequencing and cloning directly on clinical samples suggest that the mutant emerged de novo.
SUBMITTER: Inoue M
PROVIDER: S-EPMC3294403 | biostudies-literature |
REPOSITORIES: biostudies-literature
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