Role of (p)ppGpp in biofilm formation by Enterococcus faecalis.
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ABSTRACT:
SUBMITTER: Chavez de Paz LE
PROVIDER: S-EPMC3294496 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
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Role of (p)ppGpp in biofilm formation by Enterococcus faecalis.
Chávez de Paz Luis E LE Chávez de Paz Luis E LE Lemos José A JA Wickström Claes C Sedgley Christine M CM
Applied and environmental microbiology 20111216 5
Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient ΔrelA, ΔrelQ, and ΔrelA ΔrelQ mutants were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time and expressed abundant proteolytic activity. ...[more]
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