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The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer.


ABSTRACT: We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

SUBMITTER: Kang J 

PROVIDER: S-EPMC3295104 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer.

Kang Jieun J   Jones Kathleen R KR   Jang Sungil S   Olsen Cara H CH   Yoo Yun-Jung YJ   Merrell D Scott DS   Cha Jeong-Heon JH  

Journal of clinical microbiology 20120111 3


We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes. ...[more]

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