Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes.
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ABSTRACT:
SUBMITTER: Guttula SV
PROVIDER: S-EPMC3296213 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes.
Guttula Satya Vani SV Allam Apparao A Gumpeny R Sridhar RS
International journal of Alzheimer's disease 20120214
Alzheimer is characterized by the presence of senile plaques and neurofibrillary tangles in cortical regions of the brain. The experimental data is taken from Gene Expression Omnibus. A hierarchical Cluster analysis and TreeView were performed to group genes on the basis of the expression pattern. The dynamic change of expression over time and diverse patterns of expression support the concept of a complex local milieu. TreeView allows the organized data to be visualized. List of 24 genes were o ...[more]
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