Ontology highlight
ABSTRACT:
SUBMITTER: Testa JS
PROVIDER: S-EPMC3297201 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Testa James S JS Shetty Vivekananda V Sinnathamby Gomathinayagam G Nickens Zacharie Z Hafner Julie J Kamal Shivali S Zhang Xianchao X Jett Marti M Philip Ramila R
The Journal of infectious diseases 20120113 4
Dengue fever and dengue hemorrhagic fever are significant global public health problems, and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive T-cell responses. Currently, there are no available tools to assess protective T-cell resp ...[more]