Ontology highlight
ABSTRACT:
SUBMITTER: Richards DM
PROVIDER: S-EPMC3297577 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Richards David M DM Hempel Antje M AM Flärdh Klas K Buttner Mark J MJ Howard Martin M
PLoS computational biology 20120308 3
Many filamentous organisms, such as fungi, grow by tip-extension and by forming new branches behind the tips. A similar growth mode occurs in filamentous bacteria, including the genus Streptomyces, although here our mechanistic understanding has been very limited. The Streptomyces protein DivIVA is a critical determinant of hyphal growth and localizes in foci at hyphal tips and sites of future branch development. However, how such foci form was previously unknown. Here, we show experimentally th ...[more]