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Polyaspartamide Vesicle induced by Metallic Nanoparticles.

ABSTRACT: Polymer vesicles are being extensively studied to emulate self-assembly in biological systems and also use them in a variety of biological and industrial applications. This study demonstrates a novel strategy to prepare polymer vesicles in a pure aqueous medium by driving the micelle-to-vesicle transition with metallic nanoparticles. We synthesized poly(2-amino-2-hydroxyethyl aspartamide) (PAHA) substituted with octadecyl chains, which could form micelle-like self-aggregates in the aqueous medium and chemically bind with platinum precursors. Then, in situ polymerization of Pt nanoparticles within the PAHA self-aggregates generated polymer vesicles that possess nanoparticles within bilayers, because of the increase of the hydrophilic mass ratio to total mass of PAHA, f (w). This new strategy to prepare polymer vesicles would greatly serve to facilitate the control of self-assembly and ultimately improve the functionality of a wide array of polymer vesicles.

SUBMITTER: Jeong JH

PROVIDER: S-EPMC3298412 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Polyaspartamide Vesicle induced by Metallic Nanoparticles.

Jeong Jae Hyun JH Cha Chaenyung C Kaczmarowski Amy A Haan John J Oh Soonnam S Kong Hyunjoon H

Soft matter 20120101 8

Polymer vesicles are being extensively studied to emulate self-assembly in biological systems and also use them in a variety of biological and industrial applications. This study demonstrates a novel strategy to prepare polymer vesicles in a pure aqueous medium by driving the micelle-to-vesicle transition with metallic nanoparticles. We synthesized poly(2-amino-2-hydroxyethyl aspartamide) (PAHA) substituted with octadecyl chains, which could form micelle-like self-aggregates in the aqueous mediu ...[more]

PMID: 22423249

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