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Cocoa intake and arterial stiffness in subjects with cardiovascular risk factors.


ABSTRACT: To analyze the relationship of cocoa intake to central and peripheral blood pressure, arterial stiffness, and carotid intima-media thickness in subjects with some cardiovascular risk factor.A cross-sectional study of 351 subjects (mean age 54.76 years, 62.4% males).Intake of cocoa and other foods using a food frequency questionnaire, central and peripheral (ambulatory and office) blood pressure, central and peripheral augmentation index, pulse wave velocity, ambulatory arterial stiffness index, carotid intima-media thickness, and ankle-brachial index.Higher pulse wave velocity and greater cardiovascular risk were found in non-cocoa consumers as compared to high consumers (p < 0.05). In a multivariate analysis, these differences disappeared after adjusting for age, gender, the presence of diabetes, systolic blood pressure and antihypertensive and lipid-lowering drug use. All other arterial stiffness measures (central and peripheral augmentation index, ambulatory arterial stiffness index, ankle-brachial index, and carotid intima-media thickness) showed no differences between the different consumption groups.In subjects with some cardiovascular risk factors, cocoa consumption does not imply improvement in the arterial stiffness values.Clinical Trials.gov Identifier: NCT01325064.

SUBMITTER: Recio-Rodriguez JI 

PROVIDER: S-EPMC3299654 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Cocoa intake and arterial stiffness in subjects with cardiovascular risk factors.

Recio-Rodríguez José Ignacio JI   Gómez-Marcos Manuel A MA   Patino-Alonso María C MC   Agudo-Conde Cristina C   Rodríguez-Sánchez Emiliano E   García-Ortiz Luis L  

Nutrition journal 20120210


<h4>Background</h4>To analyze the relationship of cocoa intake to central and peripheral blood pressure, arterial stiffness, and carotid intima-media thickness in subjects with some cardiovascular risk factor.<h4>Findings</h4><h4>Design</h4>A cross-sectional study of 351 subjects (mean age 54.76 years, 62.4% males).<h4>Measurements</h4>Intake of cocoa and other foods using a food frequency questionnaire, central and peripheral (ambulatory and office) blood pressure, central and peripheral augmen  ...[more]

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