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Complete genome sequence of a porcine epidemic diarrhea virus variant.

ABSTRACT: In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were detected in samples (feces or small intestines) from most farms. In order to investigate whether there is a PEDV variant circulating in China, we sequenced and analyzed the complete genome of the recently identified field strain, CH/FJND-3/2011. The sequence data indicate that this PEDV variant prevails in China.

SUBMITTER: Chen J

PROVIDER: S-EPMC3302349 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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Complete genome sequence of a porcine epidemic diarrhea virus variant.

Chen Jianfei J Liu Xiaozhen X Shi Da D Shi Hongyan H Zhang Xin X Feng Li L

Journal of virology 20120301 6

In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were detected in samples (feces or small intestines) from most farms. In order to investigate whether there is a PEDV variant circulating in China, we sequenced and anal ...[more]

PMID: 22354946

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