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Tirant, a newly discovered active endogenous retrovirus in Drosophila simulans.


ABSTRACT: Endogenous retroviruses have the ability to become permanently integrated into the genomes of their host, and they are generally transmitted vertically from parent to progeny. With the exception of gypsy, few endogenous retroviruses have been identified in insects. In this study, we describe the tirant endogenous retrovirus in a subset of Drosophila simulans natural populations. By focusing on the envelope gene, we show that the entire retroviral cycle (transcription, translation, and retrotransposition) can be completed for tirant within one population of this species.

SUBMITTER: Akkouche A 

PROVIDER: S-EPMC3302509 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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tirant, a newly discovered active endogenous retrovirus in Drosophila simulans.

Akkouche Abdou A   Rebollo Rita R   Burlet Nelly N   Esnault Caroline C   Martinez Sonia S   Viginier Barbara B   Terzian Christophe C   Vieira Cristina C   Fablet Marie M  

Journal of virology 20120125 7


Endogenous retroviruses have the ability to become permanently integrated into the genomes of their host, and they are generally transmitted vertically from parent to progeny. With the exception of gypsy, few endogenous retroviruses have been identified in insects. In this study, we describe the tirant endogenous retrovirus in a subset of Drosophila simulans natural populations. By focusing on the envelope gene, we show that the entire retroviral cycle (transcription, translation, and retrotrans  ...[more]

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