Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans.
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ABSTRACT:
SUBMITTER: Muegge BD
PROVIDER: S-EPMC3303602 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Publications
Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans.
Muegge Brian D BD Kuczynski Justin J Knights Dan D Clemente Jose C JC González Antonio A Fontana Luigi L Henrissat Bernard B Knight Rob R Gordon Jeffrey I JI
Science (New York, N.Y.) 20110501 6032
Coevolution of mammals and their gut microbiota has profoundly affected their radiation into myriad habitats. We used shotgun sequencing of microbial community DNA and targeted sequencing of bacterial 16S ribosomal RNA genes to gain an understanding of how microbial communities adapt to extremes of diet. We sampled fecal DNA from 33 mammalian species and 18 humans who kept detailed diet records, and we found that the adaptation of the microbiota to diet is similar across different mammalian line ...[more]
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