Ontology highlight
ABSTRACT:
SUBMITTER: Katz TC
PROVIDER: S-EPMC3306604 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Katz Tamar C TC Singh Manvendra K MK Degenhardt Karl K Rivera-Feliciano José J Johnson Randy L RL Epstein Jonathan A JA Tabin Clifford J CJ
Developmental cell 20120301 3
The proepicardial organ is an important transient structure that contributes cells to various cardiac lineages. However, its contribution to the coronary endothelium has been disputed, with conflicting data arising in chick and mouse. Here we resolve this conflict by identifying two proepicardial markers, Scleraxis (Scx) and Semaphorin3D (Sema3D), that genetically delineate heretofore uncharacterized proepicardial subcompartments. In contrast to previously fate-mapped Tbx18/WT-1-expressing cells ...[more]