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Mediators of ocular angiogenesis.


ABSTRACT: Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade.

SUBMITTER: Qazi Y 

PROVIDER: S-EPMC3306772 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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Mediators of ocular angiogenesis.

Qazi Yureeda Y   Maddula Surekha S   Ambati Balamurali K BK  

Journal of genetics 20091201 4


Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we discuss the roles of both pro-angiogenic and anti-angiogenic molecular players in corneal angiogenesis, proliferative diabetic retinopathy, exudative macular degeneration and retinopathy of prematurity, highlighting novel targets that have emerged over the past decade. ...[more]

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