Ontology highlight
ABSTRACT:
SUBMITTER: Lu C
PROVIDER: S-EPMC3306923 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Journal of toxicology 20120201
We illustrated the development of a simple pharmacokinetic (SPK) model aiming to estimate the absorbed chlorpyrifos doses using urinary biomarker data, 3,5,6-trichlorpyridinol as the model input. The effectiveness of the SPK model in the pesticide risk assessment was evaluated by comparing dose estimates using different urinary composite data. The dose estimates resulting from the first morning voids appeared to be lower than but not significantly different to those using before bedtime, lunch o ...[more]