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Computational and statistical approaches to analyzing variants identified by exome sequencing.


ABSTRACT: New sequencing technology has enabled the identification of thousands of single nucleotide polymorphisms in the exome, and many computational and statistical approaches to identify disease-association signals have emerged.

SUBMITTER: Stitziel NO 

PROVIDER: S-EPMC3308043 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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Computational and statistical approaches to analyzing variants identified by exome sequencing.

Stitziel Nathan O NO   Kiezun Adam A   Sunyaev Shamil S  

Genome biology 20110914 9


New sequencing technology has enabled the identification of thousands of single nucleotide polymorphisms in the exome, and many computational and statistical approaches to identify disease-association signals have emerged. ...[more]

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