Ontology highlight
ABSTRACT:
SUBMITTER: Chinchore Y
PROVIDER: S-EPMC3309745 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Chinchore Yashodhan Y Gerber Gloria F GF Dolph Patrick J PJ
Proceedings of the National Academy of Sciences of the United States of America 20120210 10
Photoreceptor cell death accompanying many retinal degenerative disorders results in irreversible loss of vision in humans. However, the precise molecular pathway that executes cell death is not known. Our results from a Drosophila model of retinal degeneration corroborate previously reported findings that the developmental apoptotic pathway is not involved in photoreceptor cell demise. By undertaking a candidate gene approach, we find that players involved in the immune response against gram-ne ...[more]