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Rat brains also have a default mode network.


ABSTRACT: The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies.

SUBMITTER: Lu H 

PROVIDER: S-EPMC3309754 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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Rat brains also have a default mode network.

Lu Hanbing H   Zou Qihong Q   Gu Hong H   Raichle Marcus E ME   Stein Elliot A EA   Yang Yihong Y  

Proceedings of the National Academy of Sciences of the United States of America 20120221 10


The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feat  ...[more]

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