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ArraySearch: A Web-Based Genomic Search Engine.

ABSTRACT: Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or downregulated collectively. Searches can also be conducted using gene expression signatures from new experiments. This resource will empower biological researchers with a statistical method to explore expression data from their own research by comparing it with expression signatures from a large public archive.

SUBMITTER: Wilson TJ

PROVIDER: S-EPMC3310226 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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ArraySearch: A Web-Based Genomic Search Engine.

Wilson Tyler J TJ Ge Steven X SX

Comparative and functional genomics 20120304

Recent advances in microarray technologies have resulted in a flood of genomics data. This large body of accumulated data could be used as a knowledge base to help researchers interpret new experimental data. ArraySearch finds statistical correlations between newly observed gene expression profiles and the huge source of well-characterized expression signatures deposited in the public domain. A search query of a list of genes will return experiments on which the genes are significantly up- or do ...[more]

PMID: 22474412

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