Ontology highlight
ABSTRACT:
SUBMITTER: Yamamoto T
PROVIDER: S-EPMC3310277 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Yamamoto Takeshi T Tsubota Yuma Y Kodama Toshihisa T Kageyama-Yahara Natsuko N Kadowaki Makoto M
Clinical & developmental immunology 20120327
We examined whether maternal exposure to food antigens during lactation and maternal allergic status would affect the development of food allergy in offspring. OVA-sensitized or OVA-nonsensitized BALB/c female mice were exposed or unexposed to OVA during lactation. After weaning, their offspring were systemically sensitized twice with OVA and repeatedly given OVA by oral intubation. While 97.1% of the mice breastfed by OVA-nonsensitized and OVA-unexposed mothers developed allergic diarrhea, 59.7 ...[more]