Black tea polyphenols inhibit tumor proteasome activity.
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ABSTRACT:
SUBMITTER: Mujtaba T
PROVIDER: S-EPMC3310370 | biostudies-literature | 2012 Mar-Apr
REPOSITORIES: biostudies-literature
Publications
Black tea polyphenols inhibit tumor proteasome activity.
Mujtaba Taskeen T Dou Q Ping QP
In vivo (Athens, Greece) 20120301 2
Tea is a widely consumed beverage and its constituent polyphenols have been associated with potential health benefits. Although black tea polyphenols have been reported to possess potent anticancer activities, the effect of its polyphenols, theaflavins on the tumor's cellular proteasome function, an important biological target in cancer prevention, has not been carefully studied. Here black tea extract (T5550) enriched in theaflavins inhibited the chymotrypsin-like (CT) activity of the proteasom ...[more]
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