Ontology highlight
ABSTRACT:
SUBMITTER: Aquino KM
PROVIDER: S-EPMC3310706 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Aquino Kevin M KM Schira Mark M MM Robinson P A PA Drysdale Peter M PM Breakspear Michael M
PLoS computational biology 20120322 3
Functional MRI (fMRI) experiments rely on precise characterization of the blood oxygen level dependent (BOLD) signal. As the spatial resolution of fMRI reaches the sub-millimeter range, the need for quantitative modelling of spatiotemporal properties of this hemodynamic signal has become pressing. Here, we find that a detailed physiologically-based model of spatiotemporal BOLD responses predicts traveling waves with velocities and spatial ranges in empirically observable ranges. Two measurable p ...[more]