An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs.
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ABSTRACT:
SUBMITTER: Clark VC
PROVIDER: S-EPMC3311751 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
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An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs.
Clark Valerie C VC Harinantenaina Liva L Zeller Martin M Ronto William W Rocca James J Dossey Aaron T AT Rakotondravony Daniel D Kingston David G I DG Shaw Chris C
Journal of natural products 20120130 3
The skins of Madagascar poison frogs (Mantella) and certain Neotropical poison frogs (Epipedobates, Dendrobates) secrete the new bile acid tauromantellic acid (1), which was found in both wild-caught and captive-born frogs. This is the first molecule of endogenous origin detected in skin secretions from these taxa. Sucrose was also detected in secretions from wild-caught Mantella but not in captive-born frogs, suggesting a dietary origin. ...[more]
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