Design of a bovine low-density SNP array optimized for imputation.
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ABSTRACT:
SUBMITTER: Boichard D
PROVIDER: S-EPMC3314603 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Design of a bovine low-density SNP array optimized for imputation.
Boichard Didier D Chung Hoyoung H Dassonneville Romain R David Xavier X Eggen André A Fritz Sébastien S Gietzen Kimberly J KJ Hayes Ben J BJ Lawley Cynthia T CT Sonstegard Tad S TS Van Tassell Curtis P CP VanRaden Paul M PM Viaud-Martinez Karine A KA Wiggans George R GR
PloS one 20120328 3
The Illumina BovineLD BeadChip was designed to support imputation to higher density genotypes in dairy and beef breeds by including single-nucleotide polymorphisms (SNPs) that had a high minor allele frequency as well as uniform spacing across the genome except at the ends of the chromosome where densities were increased. The chip also includes SNPs on the Y chromosome and mitochondrial DNA loci that are useful for determining subspecies classification and certain paternal and maternal breed lin ...[more]
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