Ontology highlight
ABSTRACT:
SUBMITTER: Pellin D
PROVIDER: S-EPMC3314655 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Pellin Danilo D Miotto Paolo P Ambrosi Alessandro A Cirillo Daniela Maria DM Di Serio Clelia C
PloS one 20120328 3
We propose a new method for smallRNAs (sRNAs) identification. First we build an effective target genome (ETG) by means of a strand-specific procedure. Then we propose a new bioinformatic pipeline based mainly on the combination of two types of information: the first provides an expression map based on RNA-seq data (Reads Map) and the second applies principles of comparative genomics leading to a Conservation Map. By superimposing these two maps, a robust method for the search of sRNAs is obtaine ...[more]