Unknown

Dataset Information

0

Dynamics of a supramolecular capsule assembly with pyrene.


ABSTRACT: Water-soluble octaacid cavitands (OAs) form dimeric capsules suitable for guest incorporation. Our studies reveal that the mechanism of pyrene (Py) binding involves the rapid (<1 ms) formation of the Py·OA complex followed by slower binding with the second OA. The dissociation of the capsular OA·Py·OA complex occurs with a lifetime of 2.7 s, which is 5 orders of magnitude slower than the microsecond opening/closing ("breathing") previously observed to provide access of small molecules to the encapsulated guest. These different dynamics of the capsules have a potential impact on how the chemistry of included guests could be altered.

SUBMITTER: Tang H 

PROVIDER: S-EPMC3315598 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Dynamics of a supramolecular capsule assembly with pyrene.

Tang Hao H   de Oliveira Carla Santos CS   Sonntag Gage G   Gibb Corinne L D CL   Gibb Bruce C BC   Bohne Cornelia C  

Journal of the American Chemical Society 20120319 12


Water-soluble octaacid cavitands (OAs) form dimeric capsules suitable for guest incorporation. Our studies reveal that the mechanism of pyrene (Py) binding involves the rapid (<1 ms) formation of the Py·OA complex followed by slower binding with the second OA. The dissociation of the capsular OA·Py·OA complex occurs with a lifetime of 2.7 s, which is 5 orders of magnitude slower than the microsecond opening/closing ("breathing") previously observed to provide access of small molecules to the enc  ...[more]

Similar Datasets

| S-EPMC10566252 | biostudies-literature
| S-EPMC5454539 | biostudies-literature
| S-EPMC6078381 | biostudies-literature
| S-EPMC8529656 | biostudies-literature
| S-EPMC6750118 | biostudies-other
| S-EPMC3609949 | biostudies-literature
| S-EPMC5321526 | biostudies-literature
| S-EPMC6473331 | biostudies-literature
| S-EPMC1144740 | biostudies-other
| S-EPMC6150046 | biostudies-other