Prevalidation of salivary biomarkers for oral cancer detection.
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ABSTRACT:
SUBMITTER: Elashoff D
PROVIDER: S-EPMC3319329 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
Prevalidation of salivary biomarkers for oral cancer detection.
Elashoff David D Zhou Hui H Reiss Jean J Wang Jianghua J Xiao Hua H Henson Bradley B Hu Shen S Arellano Martha M Sinha Uttam U Le Anh A Messadi Diana D Wang Marilene M Nabili Vishad V Lingen Mark M Morris Darly D Randolph Timothy T Feng Ziding Z Akin David D Kastratovic Dragana A DA Chia David D Abemayor Elliot E Wong David T W DT
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120201 4
<h4>Background</h4>Oral cancer is the sixth most common cancer with a 5-year survival rate of approximately 60%. Presently, there are no scientifically credible early detection techniques beyond conventional clinical oral examination. The goal of this study is to validate whether the seven mRNAs and three proteins previously reported as biomarkers are capable of discriminating patients with oral squamous cell carcinomas (OSCC) from healthy subjects in independent cohorts and by a National Cancer ...[more]
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