Ontology highlight
ABSTRACT:
SUBMITTER: De Marco D
PROVIDER: S-EPMC3319592 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
De Marco Donata D Clementi Nicola N Mancini Nicasio N Solforosi Laura L Moreno Guisella J GJ Sun Xiangjie X Tumpey Terrence M TM Gubareva Larisa V LV Mishin Vasiliy V Clementi Massimo M Burioni Roberto R
PloS one 20120404 4
Influenza viruses are among the most important human pathogens and are responsible for annual epidemics and sporadic, potentially devastating pandemics. The humoral immune response plays an important role in the defense against these viruses, providing protection mainly by producing antibodies directed against the hemagglutinin (HA) glycoprotein. However, their high genetic variability allows the virus to evade the host immune response and the potential protection offered by seasonal vaccines. T ...[more]