Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei.
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ABSTRACT:
SUBMITTER: Zirlinger M
PROVIDER: S-EPMC33199 | biostudies-literature | 2001 Apr
REPOSITORIES: biostudies-literature
Publications
Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei.
Zirlinger M M Kreiman G G Anderson D J DJ
Proceedings of the National Academy of Sciences of the United States of America 20010401 9
Microarray technology represents a potentially powerful method for identifying cell type- and regionally restricted genes expressed in the brain. Here we have combined a microarray analysis of differential gene expression among five selected brain regions, including the amygdala, cerebellum, hippocampus, olfactory bulb, and periaqueductal gray, with in situ hybridization. On average, 0.3% of the 34,000 genes interrogated were highly enriched in each of the five regions, relative to the others. I ...[more]
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