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ABSTRACT:
SUBMITTER: Vella SJ
PROVIDER: S-EPMC3320108 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Vella Sarah J SJ Beattie Patrick P Cademartiri Rebecca R Laromaine Anna A Martinez Andres W AW Phillips Scott T ST Mirica Katherine A KA Whitesides George M GM
Analytical chemistry 20120302 6
This paper describes a paper-based microfluidic device that measures two enzymatic markers of liver function (alkaline phosphatase, ALP, and aspartate aminotransferase, AST) and total serum protein. A device consists of four components: (i) a top plastic sheet, (ii) a filter membrane, (iii) a patterned paper chip containing the reagents necessary for analysis, and (iv) a bottom plastic sheet. The device performs both the sample preparation (separating blood plasma from erythrocytes) and the assa ...[more]