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1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging.


ABSTRACT: Proton-based chemical shift imaging probes were encapsulated inside nano-carriers to increase the sensivitity of the reporters. Co-encapsulation with a relaxation agent results in improved sensitivity and suppresses background signals. Simultaneous imaging of different chemical shift reporters allows multiplexed detection.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC3321363 | biostudies-literature | 2012 Mar-Apr

REPOSITORIES: biostudies-literature

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1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging.

Yang Yan Y   Schühle Daniel T DT   Dai Guangping G   Alford Jamu K JK   Caravan Peter P  

Contrast media & molecular imaging 20120301 2


Proton-based chemical shift imaging probes were encapsulated inside nano-carriers to increase the sensivitity of the reporters. Co-encapsulation with a relaxation agent results in improved sensitivity and suppresses background signals. Simultaneous imaging of different chemical shift reporters allows multiplexed detection. ...[more]

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