Ontology highlight
ABSTRACT:
SUBMITTER: Ehrenreich H
PROVIDER: S-EPMC3321813 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Ehrenreich Hannelore H Kästner Anne A Weissenborn Karin K Streeter Jackson J Sperling Swetlana S Wang Kevin K KK Worthmann Hans H Hayes Ronald L RL von Ahsen Nico N Kastrup Andreas A Jeromin Andreas A Herrmann Manfred M
Molecular medicine (Cambridge, Mass.) 20110902 11-12
The German Multicenter EPO Stroke Trial, which investigated safety and efficacy of erythropoietin (EPO) treatment in ischemic stroke, was formally declared a negative study. Exploratory subgroup analysis, however, revealed that patients not receiving thrombolysis most likely benefited from EPO during clinical recovery, a result demonstrated in the findings of the Göttingen EPO Stroke Study. The present work investigated whether the positive signal on clinical outcome in this patient subgroup was ...[more]