Ontology highlight
ABSTRACT:
SUBMITTER: Thomas JA
PROVIDER: S-EPMC3323674 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Thomas Julie A JA Weintraub Susan T ST Wu Weimin W Winkler Dennis C DC Cheng Naiqian N Steven Alasdair C AC Black Lindsay W LW
Molecular microbiology 20120320 2
Encased within the 280 kb genome in the capsid of the giant myovirus φKZ is an unusual cylindrical proteinaceous 'inner body' of highly ordered structure. We present here mass spectrometry, bioinformatic and biochemical studies that reveal novel information about the φKZ head and the complex inner body. The identification of 39 cleavage sites in 19 φKZ head proteins indicates cleavage of many prohead proteins forms a major morphogenetic step in φKZ head maturation. The φKZ head protease, gp175, ...[more]