Ontology highlight
ABSTRACT:
SUBMITTER: Boone LR
PROVIDER: S-EPMC3324859 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Boone Lindsey R LR Lagor William R WR Moya Margarita de la Llera Mde L Niesen Melissa I MI Rothblat George H GH Ness Gene C GC
Atherosclerosis 20110506 1
<h4>Objective</h4>The goal of this study was to examine the effects of thyroid hormone status on the ability of serum to accept cellular cholesterol.<h4>Methods and results</h4>Sera from hypophysectomized rats treated ± T(3) was used to evaluate the role of thyroid hormone on serum efflux capacity. 2D-DIGE analysis of serum proteins showed that T(3) treated rats had increased ApoA-I, ApoA-IV and fetuin A levels with decreased Apo E levels. Microarray and real-time RT-PCR analysis of rat liver re ...[more]