Ontology highlight
ABSTRACT:
SUBMITTER: Rafikov R
PROVIDER: S-EPMC3326601 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
The Journal of endocrinology 20110603 3
Rather than being a constitutive enzyme as was first suggested, endothelial nitric oxide synthase (eNOS) is dynamically regulated at the transcriptional, posttranscriptional, and posttranslational levels. This review will focus on how changes in eNOS function are conferred by various posttranslational modifications. The latest knowledge regarding eNOS targeting to the plasma membrane will be discussed as the role of protein phosphorylation as a modulator of catalytic activity. Furthermore, new d ...[more]