Ontology highlight
ABSTRACT:
SUBMITTER: Ausin I
PROVIDER: S-EPMC3329499 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Ausin Israel I Greenberg Maxim V C MV Li Carey Fei CF Jacobsen Steven E SE
Epigenetics 20120101 1
Cytosine DNA methylation is an epigenetic mark frequently associated with silencing of genes and transposons. In Arabidopsis, the establishment of cytosine DNA methylation is performed by DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2). DRM2 is guided to target sequences by small interfering RNAs (siRNAs) in a pathway termed RNA-directed DNA methylation (RdDM). We performed a screen for mutants that affect the establishment of DNA methylation by investigating genes that contain predicted RNA-inter ...[more]