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Transcriptional enhancers in development and disease.


ABSTRACT: Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.

SUBMITTER: Sakabe NJ 

PROVIDER: S-EPMC3334578 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Transcriptional enhancers in development and disease.

Sakabe Noboru Jo NJ   Savic Daniel D   Nobrega Marcelo A MA  

Genome biology 20120123 1


Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease. ...[more]

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