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Uberon, an integrative multi-species anatomy ontology.

ABSTRACT: We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cross-species inference. It uses novel methods for representing taxonomic variation, and has proved to be essential for translational phenotype analyses. Uberon is available at http://uberon.org.

SUBMITTER: Mungall CJ

PROVIDER: S-EPMC3334586 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Uberon, an integrative multi-species anatomy ontology.

Mungall Christopher J CJ Torniai Carlo C Gkoutos Georgios V GV Lewis Suzanna E SE Haendel Melissa A MA

Genome biology 20120131 1

We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cros ...[more]

PMID: 22293552

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