Ontology highlight
ABSTRACT:
SUBMITTER: Kubicek J
PROVIDER: S-EPMC3334905 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Kubicek Jan J Schlesinger Ramona R Baeken Christian C Büldt Georg G Schäfer Frank F Labahn Jörg J
PloS one 20120419 4
We investigated in meso crystallization of membrane proteins to develop a fast screening technology which combines features of the well established classical vapor diffusion experiment with the batch meso phase crystallization, but without premixing of protein and monoolein. It inherits the advantages of both methods, namely (i) the stabilization of membrane proteins in the meso phase, (ii) the control of hydration level and additive concentration by vapor diffusion. The new technology (iii) sig ...[more]